Welcome to the Tavares Lab!

We investigate the molecular mechanisms that control craniofacial development and the genetic basis of craniofacial birth defects.

Our research focuses on the transcription factor SIX1 and SIX1-associated genes. Using transgenic mice, Xenopus (frog), and cell culture, we are defining how the SIX1 transcriptional complex controls development of the jaws, calvaria, inner ear, and teeth.

Our long-term goal is to help patients and their families understand the genetic causes of SIX1-related birth defects (e.g., branchio-oto-renal syndrome, craniosynostosis), and to develop preventive and corrective strategies.